Mr. Tom Gilbert, Senior Scientist
Mr. Gilbert plays a key role in the management of rodent toxicity and efficacy studies at RDDT Laboratories. Mr. Gilbert has a B.Sc. (Hons) awarded by the Australian National University in 2000. His research experience includes an appointment within the Centre for Inflammatory Diseases at Monash University and a role as a founding scientist at Cortical Pty Ltd. In these organisations he was involved in the validation and performance of various rodent models of inflammatory disease. Mr. Gilbert subsequently joined RDDT Laboratories in mid-2006 and has responsibility for the daily coordination of studies ranging from acute efficacy and toxicity studies to 13 week repeat dose toxicity studies.
Ms. Ling Ling Shen, Senior Scientist
Ms. Shen has engaged in the field of safety toxicology and safety pharmacology for 15 years. She achieved sound knowledge through 8 year's undergraduate and postgraduate studies in medical sciences. Her Masters Degree study and the followed further researches resulted in the registration of a Chinese complimentary medicine in China. Ms. Shen has experiences on a wide range of regulatory toxicity testing, especially in genetic toxicity testing. She has firm understanding on drug safety regulations and is familiar with various drug registration requirements. Ms. Shen has been working in the GLP environment in this organization since its very beginning.
Dr. Paul O'Leary, Senior Scientist
Dr. O'Leary has high levels of expertise and over 14 years experience in many aspects of drug discovery and development, including analytical chemistry techniques, pharmacokinetic characterisation, pharmacological efficacy, drug formulation and stability testing, molecular modelling and chemical synthesis. Dr. O'Leary obtained his Ph.D. at The University of Melbourne, and during the latter part of his studies co-founded a start-up biotech company to commercialise some of the intellectual property generated. Dr. O'Leary joined the Bioanalytical Team at RDDT Laboratories as a Senior Scientist after heading up a laboratory in a small Australian pharmaceutical company that at the time was primarily focussed on pharmacokinetic projects. Dr. O'Leary brings significant expertise in pharmacokinetic experimentation, pharmacokinetic sample preparation and LC-MS/MS analysis to the RDDT Laboratories' scientific team.
Dr. Dean Whelan, Senior Scientist
Dr Dean Whelan commenced his career in 1998 and has worked with a variety of scientific organisations, including the State Chemistry Laboratories, the Biomolecular Research Institute (BRI) and the CSIRO (Health Sciences and Nutrition Division). Working on the regulation of the hypoxic response pathway through the identification of factors that sense local oxygen concentration and relate O2 levels to hypoxia-inducible transcription factor (HIF) activity, Dean utilised mass spectrometry to identify an asparagine hydroxylation involved in the regulation of HIF transcriptional activity. Dean then returned to study and undertook a PhD at the Monash Institute of Medical Research (MIMR), Monash University. His PhD focussed on profiling the surface proteome of sperm and characterising the protein interactions of the gametes. Prior to joining the Bioanalytical Team at RDDT Laboratories, Dean worked as a senior scientist in the analytical biochemistry group of the research and development department at CSL Limited.